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Fred Hutchinson Cancer Research Center 

Description

Fred Hutchinson Cancer Research Center has been renowned as one of the world’s preeminent biomedical research institutions beginning in the late 1970s with Dr. Donnall Thomas’ Nobel Prize winning development of bone marrow transplant therapy, which continues to save innumerable lives. Our expertise in fundamental science, clinical research, infectious diseases, vaccine development, and public health science focuses on the prevention, early detection and treatment of cancer, but has broadened in scope to include other life-threatening diseases as well. The Hutchinson Center has been a preeminent force in HIV/AIDS research well before our selection as the global headquarters for the HIV Vaccine Trials Network in 2000. Our research extends to such grave diseases as sickle cell anemia, lupus, multiple sclerosis, muscular dystrophy, rheumatoid arthritis, scleroderma and Huntington’s disease. In addition to our disease-specific biomedical research projects, the following paragraphs highlight several of Fred Hutch’s excellent patient-oriented programs and a unique science teacher training partnership, all designed to reach out to you, our surrounding community.  

Mission Statement
Fred Hutchinson Cancer Research Center's mission is to eliminate cancer and related diseases as causes of human suffering and death.
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Fred Hutchinson Cancer Research Center
Mail Stop J5-200 
Seattle 
WA
98109-1024 
(206) 667-4399 

Larry Corey, M.D. 
President and Director 

Programs

Fred Hutchinson Cancer Research Center Programs

Fred Hutch Outreach Programs

Helping Washington State Science Teachers 
Our Science Education Partnership (SEP) began in 1991 to support science education for both public and private secondary school students in the most powerful  manner – by educating and equipping their classroom teachers. It is one of the nation’s most effective programs, reaching more than 30,000 students per year. Each summer, Washington state science teachers enroll in our three-week intensive session, which offers them the opportunity to work on laboratory projects with mentors, develop specific curricula, and access crucial materials for the school year. The program is particularly important for underfunded science classes that may lack the most basic educational tools. Once teachers have participated in SEP, they may continue to borrow “kits” to perform experiments in their classrooms - these sophisticated materials prepare students to transition to college level laboratory experiments. With current state cuts in the number of skilled teachers and materials, SEP fills an increasingly crucial role in preparing students for college.       

Survivorship Program
Designated in 2006 by the Lance Armstrong Foundation as one of only eight national LIVESTRONG Survivorship Centers of Excellence, the Fred Hutchinson Cancer Research Center Survivorship Program offers high quality, comprehensive services to cancer survivors through a network of community-based survivorship affiliated programs, with an emphasis on providing equal access to all cancer survivors by narrowing socio-economic, information and geographic barriers. The Survivorship Program offers clinical services, patient education and health promotion, support groups and counseling, community outreach and research. The Program welcomes all survivors, regardless of whether their cancers were diagnosed or treated here or at another center.    

Cancer Health Disparities Initiative
The Fred Hutch website provides excellent information; from disease descriptions, to our research fields, to publications designed for both lay and scientific readers. In addition, we are enhancing our outreach efforts to speak more effectively to society’s most vulnerable. Without access to accurate information about disease prevention or cancer symptoms, an alarming number of these individuals do not visit a doctor when their cancer could be successfully treated. Several of our existing programs have been providing outreach to Native American, Hispanic and African American communities, as well as more disease-specific education such as the prevention of Hepatitis B - but these are just the start. Fred Hutch’s dedication to collaborations between vastly diverse scientists has been a hallmark of our success. This same approach will help us strengthen and increase partnerships with community health organizations serving vulnerable populations and also enable us to reach out more directly and effectively to underserved individuals.

Improving Public Health Through Prevention and Intervention
The Hutchinson Center’s researchers continue to discover strategies to reduce the incidence of and mortality from cancer and other diseases. For example, Fred Hutch was the coordinating center for the Women’s Health Initiative (WHI); a 15-year study that focused on strategies for preventing heart disease, breast and colorectal cancer and osteoporosis in more than 160,000 postmenopausal women. Among the WHI’s landmark findings was demonstrating the adverse effects of combination hormone-replacement therapy on both the risk of breast cancer and cardiovascular disease in the majority of postmenopausal women. This knowledge has led to major changes in health services worldwide – it is estimated that annually, approximately 15,000 women are spared from developing invasive breast cancer in the U.S. alone as a result of changes in hormone therapy use. The data collected from the WHI continue to serve as a foundation for many on-going Fred Hutch projects devoted to improving women’s health throughout the world. The Hutchinson Center’s Cancer Prevention Program is home to scientists whose discoveries laid the groundwork for the vaccine for human papillomavirus, a principal cause of cervical cancer. These collaborations are examples of a wide array of public health projects originated by Fred Hutch researchers to share with the public and clinicians about prevention, early detection, and new, effective therapies that improve health care practices and save lives.

Recent Successes and Current Challenges

Under the leadership of President and Director Dr. Larry Corey, an internationally renowned expert in virology, immunology and vaccine development, Fred Hutch is continuing its peerless research in the discovery and development of treatments for cancer and many life-threatening diseases on a national and global basis. Dr. Corey has spear-headed a wholly unique type of collaboration among cancer centers by uniting a Fred Hutch research team with the Uganda Cancer Center, forming the UCI/Hutchinson Center Cancer Alliance – a wholly unique type of opportunity for scientist clinicians to study the causes, biology, treatment and prevention of pathogen-associated cancers in a region where six of the ten most common cancers are caused by infectious disease. Dr. Corey is challenging our investigators to think beyond any pre-conceived limitations and aim for bold, new transformative breakthroughs. Cross-disciplinary specialists are focusing on large scale research in areas such as immunotherapy, pancreatic cancer, colorectal cancer, gene-targeted correction, cancer vaccines and cancer genomics.  

As testament to our scientific excellence, among independent research institutions, Fred Hutch is consistently one of the top recipients of funding from the National Institutes of Health. This bedrock of support has contributed to our numerous cancer-research accomplishments over the past three decades. However, today the pace and potential of research has accelerated vastly and cannot be supported by government awards alone; a situation exacerbated by the flattening and future reductions in scientific research grants proposed by Congress for the NIH budget. As an independent institution, Fred Hutch’s revenue does not rely upon state support, in-patient hospital fees or student tuition – gifts from our community and grants are exceptionally important now to compensate for the decline in our sizeable historic federal support.

Learn more about Fred Hutch’s recent accomplishments at:

http://www.fhcrc.org/content/public/en/diseases/research-highlights.html.

Evaluation



Fred Hutchinson Cancer Research Center (FHCRC) advances the prevention, diagnosis and treatment of cancer, HIV/AIDS and other life-threatening diseases.

Proven Success
Since its inception in 1975, FHCRC has been world renowned for its accomplishments in prevention, early detection and life saving treatments of cancer and related serious diseases. Donnall Thomas’ revolutionary and Nobel Prize winning development of bone marrow transplantation raised survivorship from barely 10% to over 80%.

FHCRC is committed to discovering treatment methods for blood cancers including more tolerable therapies as well as ways to eliminate deadly post-transplant conditions. Center discoveries have led to a number of prevention and early detection approaches that continue to save lives.

The Public Health Sciences Division played a leading role in the 15-year Women’s Health Initiative study, which discovered that hormone-replacement therapy can increase a woman's risk of breast cancer, stroke and heart disease.

The Center’s many investigations and collaborations in cancer and HIV/AIDS research have had a significant global impact. In 2009 FHCRC received a $500,000 grant from the United States Agency for International Development and a subsequent grant in 2010 for $900,000 to aid in the construction of this first American-sponsored cancer clinic and medical-training facility in Africa. 

Collaboration
FHCRC trains clinicians from around the world in the bone marrow transplant technology in order to equip as many major hospitals as possible to serve patients.

The Seattle Cancer Care Alliance (SCCA) is a cancer treatment center that unites doctors from FHCRC, University of Washington Medicine and Seattle Children’s. It is an independent organization located on the FHCRC campus that combines over 400 faculty specializing in clinical and public health sciences with the collective aim of accelerating research progress and developing premier programs that encompass many types of cancers.

Sustainability
The Center attracts world class researchers needed to accomplish its mission. Their faculty includes three Nobel laureates.

FHCRC announced the purchase of the 5-story 1100 Eastlake Building in December 2010 and have plans to expand the current campus.


Grant History with The Seattle Foundation:

Grants Awarded through The Seattle Foundation Grantmaking Program:

DateAmountPurpose
12/11/2011 $18,879.00purchase a QuantaMaster 40 Spectrofluorometer suite.
12/11/2010 $30,000.00purchase a Roche xCelligence Real-Time Cell Analyzer System DP.
12/11/2009 $24,706.00support the purchase of a WAVE Bioreactor system.
12/11/2008 $25,000.00purchase a Nikon Eclipse Ti Fluorescence Microscopy Suite.
12/11/2007 $20,000.00purchase a Miltenyi AutoMACS Pro cell sorter.

Financials

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